The effects of novokinin, an AT2 agonist, on blood pressure, vascular responses, and levels of ADMA, NADPH oxidase, and Rho kinase in hypertension induced by NOS inhibition and salt | Zendy

Emre Mutlu | Zendy; Selçuk İlhan | Zendy; Elif Onat | Zendy; Murat Kara | Zendy; Engin Şahna | Zendy

Open Access

The effects of novokinin, an AT2 agonist, on blood pressure, vascular responses, and levels of ADMA, NADPH oxidase, and Rho kinase in hypertension induced by NOS inhibition and salt

Author(s) -

Emre Mutlu,

Selçuk İlhan,

Elif Onat,

Murat Kara,

Engin Şahna

Publication year - 2016

Publication title -

turkish journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.277

H-Index - 27

eISSN - 1303-6165

pISSN - 1300-0144

DOI - 10.3906/sag-1502-18

Subject(s) - medicine , endocrinology , enos , blood pressure , agonist , angiotensin ii , nadph oxidase , rho associated protein kinase , renin–angiotensin system , acetylcholine , receptor , nitric oxide , kinase , nitric oxide synthase , oxidative stress , biochemistry , chemistry

The effects of AT2 receptor agonist novokinin on blood pressure, eNOS, NADPH oxidase, protein arginine methyltransferases (PRMTs), and Rho kinase in hypertension were investigated. Furthermore, in isolated thoracic aorta rings, contractile and dilator responses were studied.

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