Evaluation of maternal serum folate, vitamin B12, and homocysteine levels andfactor V Leiden, factor II g.20210G>A, and MTHFR variations in prenatallydiagnosed neural tube defects | Zendy

Hatip Aydın | Zendy; Resul Arısoy | Zendy; Ali̇ Karaman | Zendy; Emre Erdoğdu | Zendy; Arda Çetinkaya | Zendy; Bilge Geçkinli | Zendy; Hasan Şimşek | Zendy; Oya Demirci | Zendy

Open Access

Evaluation of maternal serum folate, vitamin B12, and homocysteine levels andfactor V Leiden, factor II g.20210G>A, and MTHFR variations in prenatallydiagnosed neural tube defects

Author(s) -

Hatip Aydın,

Resul Arısoy,

Ali̇ Karaman,

Emre Erdoğdu,

Arda Çetinkaya,

Bilge Geçkinli,

Hasan Şimşek,

Oya Demirci

Publication year - 2016

Publication title -

turkish journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.277

H-Index - 27

eISSN - 1303-6165

pISSN - 1300-0144

DOI - 10.3906/sag-1502-128

Subject(s) - methylenetetrahydrofolate reductase , medicine , homocysteine , vitamin b12 , neural tube , etiology , thrombophilia , risk factor , factor v leiden , gastroenterology , endocrinology , thrombosis , genetics , genotype , venous thrombosis , biology , gene , embryo

Neural tube defects (NTDs) are common congenital malformations that develop as a result of interactions between several genes and environmental factors. Many factors have been investigated in order to understand the etiology of NTDs, and many studies have identified folate intake as a common contributing factor. The exact etiology of the disease is still unknown.

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