Open AccessPromoter methylation profile of GSTP1 and RASSF1A in prostate cancerand benign hyperplasia in Vietnamese men
Author(s) -
Thi Thuong Lan Vo,
Bich Thuan Ta,
Van To Ta,
Dieu Linh Vuong,
Quynh Uyen Nguyen
Publication year - 2016
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-1410-65
Subject(s) - gstp1 , methylation , prostate cancer , medicine , hyperplasia , dna methylation , prostate , biomarker , pathological , oncology , cancer , cancer research , biology , genotype , gene , genetics , gene expression
The GSTP1 and RASSF1A methylations that were considered as prostate cancer-specific molecular biomarkers have been extensively reported in Western/American patients with prostate cancer but are rarely reported in Southeast Asian patients. In the present study, the methylation status of the GSTP1 and RASSF1A promoters was evaluated in prostate cancer (PCa) and benign prostate hyperplasia (BPH) tissues from Vietnamese men.
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