Open AccessProtective effect of β-glucan on acute lung injury induced bylipopolysaccharide in rats
Author(s) -
Meryem İraz,
Mustafa Iraz,
Mukaddes Eşrefoğlu,
Mehmet Şerif Aydın
Publication year - 2015
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-1312-1
Subject(s) - medicine , procalcitonin , lipopolysaccharide , proinflammatory cytokine , lung , basal (medicine) , glucan , inflammation , gastroenterology , immunology , endocrinology , sepsis , biochemistry , biology , insulin
Lipopolysaccharide (LPS)-induced endotoxemia can cause serious organ damage such as acute lung injury and death by triggering the secretion of proinflammatory cytokines and acute-phase reactants. The goal of this study was to evaluate the effects of β-glucan on inflammatory mediator levels and histopathological changes in LPS-induced endotoxemia.
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