Analysis of vacA/cagA genotypes/status in Helicobacter pylori isolates from Iranian children and their association with clinical outcome | Zendy

Tahereh Falsafi | Zendy; Afsaneh Khani | Zendy; Fatemeh Mahjoub | Zendy; Ezat Asgarani | Zendy; Nazli Sotoudeh | Zendy

Open Access

Analysis of vacA/cagA genotypes/status in Helicobacter pylori isolates from Iranian children and their association with clinical outcome

Author(s) -

Tahereh Falsafi,

Afsaneh Khani,

Fatemeh Mahjoub,

Ezat Asgarani,

Nazli Sotoudeh

Publication year - 2015

Publication title -

turkish journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.277

H-Index - 27

eISSN - 1303-6165

pISSN - 1300-0144

DOI - 10.3906/sag-1311-2

Subject(s) - caga , histopathology , helicobacter pylori , medicine , gastritis , genotype , gastroenterology , chronic gastritis , allele , immunology , pathology , gene , biology , virulence , biochemistry

More than 50% of Iranian children are infected with Helicobacterpylori; however, no data exist about the association of vacA/cagA genotype/status with disease outcomes in them. We analyzed association of vacA/cagA genotypes/status of children's isolates with gastric inflammation status as the first step in H. pylori pathogenesis.

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