Association between maternal ghrelin levels and hyperemesis gravidarum | Zendy

İkbal Kaygusuz | Zendy; İlknur İnegöl Gümüş | Zendy; Melahat Yıldırım | Zendy; Hüsamettin Erdamar | Zendy; Aysel Uysal Derbent | Zendy; Serap Simavlı | Zendy; Abdullah Ayyıldız | Zendy; Muhammet Ramazan Yiğitoğlu | Zendy

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Association between maternal ghrelin levels and hyperemesis gravidarum

Author(s) -

İkbal Kaygusuz,

İlknur İnegöl Gümüş,

Melahat Yıldırım,

Hüsamettin Erdamar,

Aysel Uysal Derbent,

Serap Simavlı,

Abdullah Ayyıldız,

Muhammet Ramazan Yiğitoğlu

Publication year - 2013

Publication title -

turkish journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.277

H-Index - 27

eISSN - 1303-6165

pISSN - 1300-0144

DOI - 10.3906/sag-1209-9

Subject(s) - medicine , ghrelin , hyperemesis gravidarum , body mass index , hormone , endocrinology , obstetrics , physiology , vomiting

To investigate serum levels of ghrelin in pregnant women as a potential early marker for hyperemesis gravidarum (HG). Materials and methods: A cross-sectional study was carried out at Fatih University Hospital. Included in the study were 35 women with HG and 31 pregnant women without HG as a control group. The groups were compared in terms of age, gravidity, body mass index (BMI), and fasting serum thyroid-stimulating hormone (TSH) and ghrelin levels. Results: Ghrelin levels of the patients with HG were found to be significantly lower than those in the control group (P = 0.03). No intergroup differences could be found in serum TSH or BMI values . Conclusion: Ghrelin might serve as a reliable marker in the etiopathogenesis of HG.

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