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Analysis of KAL1, FGFR1, GPR54, and NELF copy number variations by multiplex ligation dependent probe amplification in male patients with idiopathic hypogonadotropic hypogonadism
Author(s) -
Yalçın Başaran,
Hilmi Umut Ünal,
Şinasi Erol Bolu,
Rahşan Ilıkçı Saǧkan,
Mustafa Çakar,
Abdullah Taşlıpınar,
Taner Özgürtaş,
Uğur Muşabak
Publication year - 2013
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-1208-1
Subject(s) - hypogonadotropic hypogonadism , kallmann syndrome , gene duplication , medicine , exon , gene , multiplex ligation dependent probe amplification , endocrinology , genetics , hormone , biology , disease , covid-19 , infectious disease (medical specialty)
Apricot germplasm collection and characterization are the essential stages of breeding programs for diversity. Traditionally, germplasm collection and characterization are performed by describing phenological, pomological, and morphological characteristics of the germplasm. In this study, 93 apricot accessions and 1 apricot × plum hybrid (Kayisi Erigi) were collected from different regions of Turkey and were evaluated for 57 morphological UPOV (International Union for the Protection of New Varieties of Plants) characteristics, along with 13 pomological traits. Turkish apricot trees were generally found to be either strong (29.8%) or very strong (54.3%). Only 12 accessions (GU-52, Canakkale, Cekirge-52, Karacabey, Gec Aprikoz, Guz Aprikozu, Alyanak, Hasanbey, Alkaya, Pasa Mismisi, Agerik, and Ziraat Okulu) had large fruits. Of the total 93 specimens, 67 accessions did not exhibit kernel bitterness. Important dried cultivars of Turkey contain more than 25% total soluble solids (TSS). The harvest period of the majority (84 accessions) started at the end of June and lasted until mid-July. Principle coordinate analysis (PCoA) and principle component analysis (PCA) revealed that eigenvalues of the first 3 components were able to represent 32.67% of total variance in PCoA and 23.63% of total variance in PCA. The eigenvalue of pomological PCA analysis was able to represent 73% of total variance. Significant negative correlations were determined among fruit juice acidity, TSS, and pH. The morphological distance index between Turkish apricots varied from 0.21 to 0.79. Information revealed in this study may be useful for both breeders and apricot breeding programs.

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