Intravenous Administration is the Best Route of Mesenchymal Stem Cells Migration in Improving Liver Function Enzyme of Acute Liver Failure
Author(s) -
Agung Putra,
Ika Rosdiana,
Dewi Masyithah Darlan,
Iffan Alif,
Fitri Hayuningtyas,
I Nyoman Wahyu Esa Wijaya,
Rita Aryanti,
Fadhli Rizal Makarim,
Arini Dewi Antari
Publication year - 2020
Publication title -
folia medica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.245
H-Index - 21
eISSN - 1314-2143
pISSN - 0204-8043
DOI - 10.3897/folmed..e47712
Subject(s) - mesenchymal stem cell , liver function , vascular endothelial growth factor , liver function tests , bilirubin , transaminase , medicine , liver regeneration , immunohistochemistry , chemistry , pharmacology , andrology , endocrinology , enzyme , regeneration (biology) , pathology , vegf receptors , biology , biochemistry , microbiology and biotechnology
Mesenchymal stem cells (MSCs) migrate and transmigrate to acute liver failure (ALF) area due to vascular endothelial growth factor (VEGF) stimulation as an attractant molecule then actively giving the paracrine signaling and or differentiating into primary hepatocytes, however the best route of MSCs transplanted to liver injury area remains unclear.
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