A case of distal extrahepatic cholangiocarcinoma with two positive resection margins | Zendy

Wayne A. Warner | Zendy; Wesley Ramcharan | Zendy; Dave Harnanan | Zendy; Srikanth Umakanthan | Zendy; Ravi Maharaj | Zendy

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A case of distal extrahepatic cholangiocarcinoma with two positive resection margins

Author(s) -

Wayne A. Warner,

Wesley Ramcharan,

Dave Harnanan,

Srikanth Umakanthan,

Ravi Maharaj

Publication year - 2016

Publication title -

oncology letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.766

H-Index - 54

eISSN - 1792-1082

pISSN - 1792-1074

DOI - 10.3892/ol.2016.5174

Subject(s) - medicine , malignancy , jaundice , bile duct , obstructive jaundice , presentation (obstetrics) , lesion , biliary tract , radiology , resection , common bile duct , general surgery , surgery , pathology

Cholangiocarcinoma is an uncommon primary malignancy of the biliary tract that is challenging to diagnose and treat effectively due to its relatively silent and late clinical presentation. The present study reports a case of a 60-year-old male with distal extrahepatic cholangiocarcinoma with a 3-week history of painless obstructive jaundice symptoms and subjective weight loss. Imaging revealed an obstructing lesion in the common bile duct, just distal to the entrance of the cystic duct. Pathology revealed moderately differentiated cholangiocarcinoma with two positive proximal resection margins. The two positive resection margins presented a challenge during surgery and points to an urgent need for further studies to better illuminate diagnostic and therapeutic options for patients with similar clinicopathological presentation.

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