Acquired amegakaryocytic thrombocytopenic purpura induced by percutaneous ethanol injection during treatment of hepatocellular carcinoma: A case report | Zendy

Ding-lun Ai | Zendy; Bingle Li | Zendy; XIAO-MING PENG | Zendy; Lin-Zhi Zhang | Zendy; Jingyan Wang | Zendy; Yun Zhao | Zendy; Bin Yang | Zendy; Qiang Yu | Zendy; Chunzi Liu | Zendy; Ning Yang | Zendy; HUA-MING WANG | Zendy; Lin Zhou | Zendy

Open Access

Acquired amegakaryocytic thrombocytopenic purpura induced by percutaneous ethanol injection during treatment of hepatocellular carcinoma: A case report

Author(s) -

Ding-lun Ai,

Bingle Li,

XIAO-MING PENG,

Lin-Zhi Zhang,

Jingyan Wang,

Yun Zhao,

Bin Yang,

Qiang Yu,

Chunzi Liu,

Ning Yang,

HUA-MING WANG,

Lin Zhou

Publication year - 2015

Publication title -

oncology letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.766

H-Index - 54

eISSN - 1792-1082

pISSN - 1792-1074

DOI - 10.3892/ol.2015.3934

Subject(s) - hepatocellular carcinoma , percutaneous ethanol injection , medicine , thrombocytopenic purpura , percutaneous , cancer research , gastroenterology , platelet , radiofrequency ablation , ablation

Percutaneous ethanol injection is an important localized treatment method for patients presenting with hepatocellular carcinoma (HCC). Among the advantages of percutaneous ethanol injection are its minimal invasiveness, simplicity, low cost and low risk of complications. However, the increasing popularity of percutaneous ethanol injection has resulted in serious adverse effects attributed to individual variations. The present study describes the case of a patient who exhibited acquired amegakaryocytic thrombocytopenic purpura, caused by percutaneous ethanol injection treatment for HCC. This complication was promptly identified, and platelet transfusion and injection of recombinant human interleukin-11 resulted in a rapid recovery of the patient's platelet count. Attention should be given to this rare complication in patients administered percutaneous ethanol injection treatment for HCC.

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