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Clear cell sarcoma of the right lumbar region: A case report and review of the literature
Author(s) -
Xueli Yang,
Lu Sanjun,
Jie Xue,
YAN-FEN WU,
Shi Jun-ling
Publication year - 2014
Publication title -
oncology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.766
H-Index - 54
eISSN - 1792-1082
pISSN - 1792-1074
DOI - 10.3892/ol.2014.2372
Subject(s) - lumbar , soft tissue , medicine , soft tissue sarcoma , sarcoma , immunohistochemistry , magnetic resonance imaging , pathology , clear cell sarcoma , radiology
Clear cell sarcoma of soft tissues is a very rare, malignant soft tissue tumor that usually arises in the extremities, with a predilection for the lower limbs. This report presents a 45-year-old male with a painless mass in the right lumbar region for one year. Magnetic resonance imaging showed a 3.6×3.2×1.5-cm soft tissue mass of the right lumbar region. The tumoral cells had pleomorphic nuclei and large amounts of clear cytoplasm, and a proportion of the cells contained melanin. Immunohistochemical analysis was performed, which identified that the cells were positive for S-100, MITF and HMB-45 tumor markers. The patient underwent a postoperative chemotherapy protocol and had no local recurrences at one year post-surgery.

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