Leukemia cutis in a patient with acute monocytic leukemia diagnosed simultaneously with hepatocellular carcinoma: A case study | Zendy

Dong Keun Seok | Zendy; Sae Yoon Kee | Zendy; Soon Young Ko | Zendy; Jung Hwa Lee | Zendy; Hye Young Kim | Zendy; In Sun Kim | Zendy; Hee Yeon Seo | Zendy

Open Access

Leukemia cutis in a patient with acute monocytic leukemia diagnosed simultaneously with hepatocellular carcinoma: A case study

Author(s) -

Dong Keun Seok,

Sae Yoon Kee,

Soon Young Ko,

Jung Hwa Lee,

Hye Young Kim,

In Sun Kim,

Hee Yeon Seo

Publication year - 2013

Publication title -

oncology letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.766

H-Index - 54

eISSN - 1792-1082

pISSN - 1792-1074

DOI - 10.3892/ol.2013.1580

Subject(s) - medicine , hepatocellular carcinoma , leukemia cutis , leukemia , pathology , acute myelomonocytic leukemia , myeloid leukemia , biopsy , acute leukemia , bone marrow , cancer research

Acute myeloid leukemia presenting as leukemia cutis (LC) with hepatocellular carcinoma is extremely rare. The current study presents a case of a 53-year-old male with generalized cutaneous nodules on the face and anterior chest wall. Laboratory tests, including bone marrow biopsy revealed acute myelomonocytic leukemia (AML-M4) with skin and tonsilar involvement. Liver magnetic resonance imaging (MRI) revealed a 6-cm mass in hepatic segments 4 and 8, and a liver biopsy demonstrated that hepatocellular carcinoma cells and immature blast cells coexisted. Although LC has been reported in Korea, a case of LC associated with acute myelomonocytic leukemia was diagnosed simultaneously with hepatocellular carcinoma and tonsillar involvement. The present study describes this case with a review of the literature.

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