Isolated solitary brain metastasis as a relapse of small cell lung cancer | Zendy

Hirofumi Sakurai | Zendy; Koichi Kurishima | Zendy; Shinsuke Homma | Zendy; Katsunori Kagohashi | Zendy; Kunihiko Miyazaki | Zendy; Mio Kawaguchi | Zendy; Hiroaki Satoh | Zendy; Nobuyuki Hizawa | Zendy

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Isolated solitary brain metastasis as a relapse of small cell lung cancer

Author(s) -

Hirofumi Sakurai,

Koichi Kurishima,

Shinsuke Homma,

Katsunori Kagohashi,

Kunihiko Miyazaki,

Mio Kawaguchi,

Hiroaki Satoh,

Nobuyuki Hizawa

Publication year - 2013

Publication title -

oncology letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.766

H-Index - 54

eISSN - 1792-1082

pISSN - 1792-1074

DOI - 10.3892/ol.2013.1489

Subject(s) - molecular medicine , brain metastasis , oncogene , lung cancer , cancer , cell cycle , cell , medicine , metastasis , oncology , cancer research , pathology , biology , genetics

The brain is one of the most common sites for the metastasis of small cell lung cancer (SCLC). The present study describes two cases of an isolated solitary brain metastasis as a relapse of SCLC, which occurred more than one year after the completion of the initial successful treatment for SCLC. The tumors were identified during a regular check-up computed tomography (CT) scan and were successfully treated. To the best of our knowledge, this is the first study to report the cases of two patients with an isolated solitary brain metastasis as a relapse of SCLC. Although extremely rare, the possibility of such recurrences should be considered, particularly in patients who have refused prophylactic cranial irradiation.

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