Open AccessCase series of cerebral infarction with Trousseau's syndrome associated with malignant gynecological tumors
Author(s) -
Masako Ishikawa,
Kentaro Nakayama,
Tomoka Ishibashi,
Emi Sato,
Kohei Nakamura,
Hiroshi Katagiri,
Satoru Kyo
Publication year - 2016
Publication title -
molecular and clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.442
H-Index - 7
eISSN - 2049-9469
pISSN - 2049-9450
DOI - 10.3892/mco.2016.888
Subject(s) - medicine , cancer , disease , ovarian cancer , cerebral infarction , malignant disease , carcinoma , thromboembolic disease , neurosurgery , ovarian carcinoma , oncogene , coagulation disorder , oncology , coagulation , pathology , surgery , thrombosis , cell cycle , ischemia
The association between neoplastic disease and thromboembolic disorders was first recognized by Trousseau in 1865. Blood coagulation abnormalities have been reported in the majority of patients with cancer, including those with ovarian carcinoma. However, Trousseau's syndrome (TS) has rarely been reported in women with ovarian carcinoma. We herein report a case series of TS, notably in the brain, in association with gynecological malignant disease, and emphasize the difficulties associated with the management of these thromboembolic effects. The aim of this study was to present our experience with 5 TS patients whose condition was effectively controlled through treatment of the primary malignant disease. Therefore, we suggest that patients with TS may be cured by tumor resection, even if they have severe thromboembolic disease, such as cerebral or pulmonary infarction.
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