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Acute transverse myelitis and subacute thyroiditis associated with dengue viral infection: A case report and literature review
Author(s) -
Zhiming Mo,
Ya-xian Dong,
Xiaolian Chen,
Huiyan Yao,
Bin Zhang
Publication year - 2016
Publication title -
experimental and therapeutic medicine
Language(s) - English
Resource type - Journals
eISSN - 1792-1015
pISSN - 1792-0981
DOI - 10.3892/etm.2016.3604
Subject(s) - dengue fever , acute transverse myelitis , medicine , methylprednisolone , plasmapheresis , subacute thyroiditis , transverse myelitis , myelitis , viral infection , immunology , thyroiditis , antibody , multiple sclerosis , virus , disease , psychiatry , spinal cord
Acute transverse myelitis is a rare manifestation of dengue infection. To the best of our knowledge, only 6 cases of acute transverse myelitis as a manifestation of dengue infection have been reported thus far. The present study described a case of acute transverse myelitis complicated with subacute thyroiditis 6 days after the onset of dengue viral infection. In addition, the available literature was searched to identify similar previous cases. Treatment with intravenous pulse methylprednisolone immunoglobulin plasmapheresis and physiotherapy resulted in partial recovery at 3 months post-infection. In conclusion, the involvement of dengue infection should be considered in patients who develop central nervous system manifestations during or after the recovery period of dengue infection. Furthermore, since methylprednisolone and immunoglobulin are effective during the active phase of the infection, prompt diagnosis and initiation of treatment are crucial.

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