Transformation Chlorophyll a of Spirulina platensis to Chlorin e6 Derivatives and Several Applications | Zendy

Hoa Thi Hai Bui | Zendy; Tam Thi Pham | Zendy; Hien Thi Thu Nguyen | Zendy; Trung Minh | Zendy; Vu Thi Nga | Zendy; Nguyen Duy Bac | Zendy; Vu Thi Huyen | Zendy; Hai Minh Le | Zendy; Quang Canh Tran | Zendy

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Transformation Chlorophyll a of Spirulina platensis to Chlorin e6 Derivatives and Several Applications

Author(s) -

Hoa Thi Hai Bui,

Tam Thi Pham,

Hien Thi Thu Nguyen,

Trung Minh,

Vu Thi Nga,

Nguyen Duy Bac,

Vu Thi Huyen,

Hai Minh Le,

Quang Canh Tran

Publication year - 2019

Publication title -

open access macedonian journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.288

H-Index - 17

ISSN - 1857-9655

DOI - 10.3889/oamjms.2019.838

Subject(s) - pheophorbide a , spirulina (dietary supplement) , hela , chlorophyll , photodynamic therapy , mtt assay , chlorin , medicine , nuclear chemistry , chlorophyll a , propionibacterium acnes , food science , botany , chemistry , biochemistry , biology , cell , organic chemistry , acne , raw material , dermatology

Spirulina platensis contains a large amount of chlorophylls, chlorophyll a, that are starting materials to synthesize functionalized chlorins. Chlorin e6 (Ce6) as well as its derivatives are second generation sensitizers using in photodynamic therapy (PDT) of various cancers. In this study, we transfer chlorophyll a of S. platensis to Ce6 derivatives and determine their several applications.

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