Effect of Levosimendan Compared to Conventional Inotropic Agents on Hemodynamics and Outcome in Patient with Poor LV Function Undergoing Cardiac Surgery | Zendy

Mahmoud Khaled | Zendy; Ahmad Naem Almogy | Zendy; Mohamed Shehata | Zendy; Fahim Ragab | Zendy; Khaled Zeineldin | Zendy

Open Access

Effect of Levosimendan Compared to Conventional Inotropic Agents on Hemodynamics and Outcome in Patient with Poor LV Function Undergoing Cardiac Surgery

Author(s) -

Mahmoud Khaled,

Ahmad Naem Almogy,

Mohamed Shehata,

Fahim Ragab,

Khaled Zeineldin

Publication year - 2019

Publication title -

open access macedonian journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.288

H-Index - 17

ISSN - 1857-9655

DOI - 10.3889/oamjms.2019.675

Subject(s) - levosimendan , medicine , inotrope , hemodynamics , cardiology , ventricular function , cardiac function curve , cardiac surgery , anesthesia , heart failure

Patients undergoing heart surgery involving cardiopulmonary bypass (CPB) experience global myocardial ischemia with subsequent reperfusion which, despite cardioplegic protection, may result in different degrees of transient ventricular dysfunction. Levosimendan is a "calcium sensitisers", it improves myocardial contractility by sensitising troponin C to calcium without increasing myocardial oxygen consumption and without impairing relaxation and diastolic function.

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