Role of Inflammation in the Pathogenesis of Diabetic Peripheral Neuropathy | Zendy

Daniela Ristikj-Stomnaroska | Zendy; Valentina Risteska-Nejasmic | Zendy; M Papazova | Zendy

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Role of Inflammation in the Pathogenesis of Diabetic Peripheral Neuropathy

Author(s) -

Daniela Ristikj-Stomnaroska,

Valentina Risteska-Nejasmic,

M Papazova

Publication year - 2019

Publication title -

open access macedonian journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.288

H-Index - 17

ISSN - 1857-9655

DOI - 10.3889/oamjms.2019.646

Subject(s) - medicine , pathogenesis , peripheral neuropathy , diabetes mellitus , inflammation , gastroenterology , peripheral , diabetic neuropathy , neuritis , tumor necrosis factor alpha , surgery , endocrinology

Diabetic peripheral neuropathy (DPN) means the presence of symptoms and/or signs of peripheral nerve damage that occur to people with diabetes, excluding all other causes of neuropathy. Chronic hyperglycaemia leads to increased secretion of tumour necrotic factor-alpha (TNF-α), with the development of micro and macroangiopathy, damage to nerve fibres and local demyelination.

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