Role of Matrix Metalloproteinase-9 in Neonatal Hypoxic-Ischemic Encephalopathy | Zendy

Mohab M. Salah | Zendy; M A Abdelmawla | Zendy; Sally R. Eid | Zendy; Rasha M. Hasanin | Zendy; Elham Mohamed Mostafa | Zendy; M W Abdelhameed | Zendy

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Role of Matrix Metalloproteinase-9 in Neonatal Hypoxic-Ischemic Encephalopathy

Author(s) -

Mohab M. Salah,

M A Abdelmawla,

Sally R. Eid,

Rasha M. Hasanin,

Elham Mohamed Mostafa,

M W Abdelhameed

Publication year - 2019

Publication title -

open access macedonian journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.288

H-Index - 17

ISSN - 1857-9655

DOI - 10.3889/oamjms.2019.618

Subject(s) - medicine , encephalopathy , hypoxic ischemic encephalopathy , ischemia , matrix metalloproteinase , gastroenterology , matrix metalloproteinase 9 , hypoxia (environmental) , brain damage , anesthesia , chemistry , organic chemistry , oxygen

Neonatal encephalopathy is a heterogeneous syndrome characterised by signs of central nervous system dysfunction in the newborn. Matrix metalloproteinase-9(MMP-9) increases the blood-brain barrier permeability, and their inhibitors can reduce its damage. MMP-9 has been implicated specifically in cerebral ischemia.

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