The Relationship between Gene Polymorphism of miRNAs Regulating FGA and Schizophrenia
Author(s) -
Bonan Cao,
Mingjia Yang,
Guojun Kang,
Rixin Li,
Xiaojing Zhu,
Qi Kang,
Yaoyao Sun,
Mingyuan Zhang,
Yueying Wang,
Xin Chen,
Qiong Yu
Publication year - 2019
Publication title -
open access macedonian journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.288
H-Index - 17
ISSN - 1857-9655
DOI - 10.3889/oamjms.2019.334
Subject(s) - international hapmap project , single nucleotide polymorphism , snp , dbsnp , polymorphism (computer science) , allele , genotype , gene , medicine , microrna , allele frequency , genetics , biology
No significant difference existed between schizophrenic patients and controls in SNP (rs2043556 and rs4909237) in the precursor region of hsa-miR-605 and pre-hsa-miR-499a/pre-hsa-miR-499b. There may not regulate FGA gene expression. Thus, hsa-miR-605 and pre-hsa-miR-499a/pre-hsa-miR-499b may not influence the risks of schizophrenia.
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