Immunohistochemical Expression of Androgen Receptors (AR) in Various Breast Cancer Subtypes | Zendy

Nour El Hoda S. Ismael | Zendy; Rasha A. Khairy | Zendy; Suzan M. Talaat | Zendy; Fatima A Abd El-Fattah | Zendy

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Immunohistochemical Expression of Androgen Receptors (AR) in Various Breast Cancer Subtypes

Author(s) -

Nour El Hoda S. Ismael,

Rasha A. Khairy,

Suzan M. Talaat,

Fatima A Abd El-Fattah

Publication year - 2019

Publication title -

open access macedonian journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.288

H-Index - 17

ISSN - 1857-9655

DOI - 10.3889/oamjms.2019.311

Subject(s) - androgen receptor , medicine , breast cancer , immunohistochemistry , immunostaining , cancer , androgen , breast carcinoma , oncology , receptor , cancer research , pathology , hormone , prostate cancer

Breast carcinoma ranks the first among malignant tumours in females and is the chief cause of cancer-related mortality. Androgen in implicated in the induction of proliferation and growth of mammary cells through binding to their corresponding receptors. Androgens influence the risk of acquiring breast cancer through either direct binding to androgen receptors (AR) or indirectly through their transformation to estradiol or competing for steroid binding proteins.

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