Association between Malondialdehyde and Glutathione (L-gamma-Glutamyl-Cysteinyl-Glycine/GSH) Levels on Workers Exposed to Benzene in Indonesia
Author(s) -
Abdul Rohim Tualeka,
Tri Martiana,
Ahsan Ahsan,
Syamsiar S. Russeng,
Wulan Meidikayanti
Publication year - 2019
Publication title -
open access macedonian journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.288
H-Index - 17
ISSN - 1857-9655
DOI - 10.3889/oamjms.2019.246
Subject(s) - glutathione , malondialdehyde , benzene , radical , medicine , thiobarbituric acid , glycine , antioxidant , biochemistry , chromatography , lipid peroxidation , enzyme , chemistry , organic chemistry , amino acid
Chemicals that enter the body, especially benzene, will undergo a detoxification process. Unfortunately, at the detoxification process, sometimes benzene can produce free radicals. Free radical oxidation of lipids produces MDA compounds (malondialdehyde). To overcome these free radicals, the body will adapt to produce Glutathione (GSH) enzymes.
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