Efficacy of Probiotic Therapy on Atopic Dermatitis in Adults Depends on the C-159T Polymorphism of the CD14 Receptor Gene - A Pilot Study
Author(s) -
Oleksandr Litus,
N. Derkach,
Віктор Літус,
Yuriy Bisyuk,
Bohdan Lytvynenko
Publication year - 2019
Publication title -
open access macedonian journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.288
H-Index - 17
ISSN - 1857-9655
DOI - 10.3889/oamjms.2019.242
Subject(s) - medicine , bifidobacterium animalis , atopic dermatitis , probiotic , lactobacillus acidophilus , gastroenterology , atopy , genotype , gene polymorphism , immunology , bifidobacterium , lactobacillus , allergy , food science , biology , gene , biochemistry , genetics , fermentation , bacteria
The C-159T polymorphism of the CD14 receptor gene can be associated with the development of atopic dermatitis. Probiotics can modulate chronic inflammation through activation of the CD14 receptor. So, the efficacy of probiotic therapy can be dependent on this genetic polymorphism.
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