Correlations between Insulin Receptor Substrate-1 with Phosphoinositide 3-Kinase and P38 Mitogen-Activated Protein Kinase Levels after Treatment of Diabetic Rats with Puguntano (Curanga Fel-Terrae [Merr.]) Leaf Extract | Zendy

Santi Syafril | Zendy; Dharma Lindarto | Zendy; Aznan Lelo | Zendy; Rosita Juwita Sembiring | Zendy; Awaluddin Saragih | Zendy

Open Access

Correlations between Insulin Receptor Substrate-1 with Phosphoinositide 3-Kinase and P38 Mitogen-Activated Protein Kinase Levels after Treatment of Diabetic Rats with Puguntano (Curanga Fel-Terrae [Merr.]) Leaf Extract

Author(s) -

Santi Syafril,

Dharma Lindarto,

Aznan Lelo,

Rosita Juwita Sembiring,

Awaluddin Saragih

Publication year - 2019

Publication title -

open access macedonian journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.288

H-Index - 17

ISSN - 1857-9655

DOI - 10.3889/oamjms.2019.218

Subject(s) - medicine , mapk/erk pathway , protein kinase a , p38 mitogen activated protein kinases , phosphoinositide 3 kinase , insulin , streptozotocin , kinase , irs1 , endocrinology , insulin receptor , insulin resistance , diabetes mellitus , intraperitoneal injection , receptor , pi3k/akt/mtor pathway , pharmacology , apoptosis , biochemistry , biology

Defects in post-receptor insulin signalling are the major cause of insulin resistance in type 2 diabetes mellitus (T2DM).

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