AM-1241 CB2 Receptor Agonist Attenuates Inflammation, Apoptosis and Stimulate Progenitor Cells in Bile Duct Ligated Rats | Zendy

Hesham Mahmoud | Zendy; Mona Osman | Zendy; Osama A. ElShabrawy | Zendy; Heba M. I. Abdallah | Zendy; Ahmed Khairallah | Zendy

Open Access

AM-1241 CB2 Receptor Agonist Attenuates Inflammation, Apoptosis and Stimulate Progenitor Cells in Bile Duct Ligated Rats

Author(s) -

Hesham Mahmoud,

Mona Osman,

Osama A. ElShabrawy,

Heba M. I. Abdallah,

Ahmed Khairallah

Publication year - 2019

Publication title -

open access macedonian journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.288

H-Index - 17

ISSN - 1857-9655

DOI - 10.3889/oamjms.2019.194

Subject(s) - medicine , liver injury , fibrosis , inflammation , agonist , receptor , progenitor cell , endocrinology , pharmacology , stem cell , biology , microbiology and biotechnology

The cannabinoid receptor 2 (CB2) plays a pleiotropic role in the innate immunity and is considered a crucial mediator of liver disease. Cannabinoid CB2 receptor activation has been reported to attenuate liver fibrosis in CCl4 exposed mice and also plays a potential role in liver regeneration in a mouse model of I/R and protection against alcohol-induced liver injury.

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