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Retrospective Analysis of Skin Toxicity in Patients under Anti-EGFR Tyrosine Kinase Inhibitors: Our Experience in Lung Cancer
Author(s) -
Maria Carmela Annunziata,
Maria Ferrillo,
Eleonora Cinelli,
Luigia Panariello,
Danilo Rocco,
Gabriella Fabbrocini
Publication year - 2019
Publication title -
open access macedonian journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.288
H-Index - 17
ISSN - 1857-9655
DOI - 10.3889/oamjms.2019.170
Subject(s) - medicine , erlotinib , afatinib , rash , lung cancer , dermatology , skin cancer , mucocutaneous zone , gefitinib , cancer , papulopustular , adverse effect , epidermal growth factor receptor , disease , rosacea , acne
Tyrosine kinase inhibitors (TKIs) have been introduced for the treatment of lung cancer, improving progression-free survival, objective response rate, and quality of life. However, TKIs can lead to cutaneous toxicities, including papulopustular rash, xerosis, paronychia with/without pyogenic granulomas, scalp disorders, facial hair and/or eyelash growth.

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