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The The Influence of Mesenchymal Stem Cell Wharton Jelly toward Prostaglandin E2 Gene Expression on Synoviocyte Cell Osteoarthritis
Author(s) -
Vivi Sofia,
Moch. Saiful Bachri,
Endrinaldi Endrinaldi
Publication year - 2019
Publication title -
open access macedonian journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.288
H-Index - 17
ISSN - 1857-9655
DOI - 10.3889/oamjms.2019.082
Subject(s) - mesenchymal stem cell , medicine , osteoarthritis , wharton's jelly , prostaglandin e2 , stem cell , gene expression , pathology , gene , biology , microbiology and biotechnology , genetics , alternative medicine
Pharmacological therapy in the management of OA causes many new health problems due to side effects caused by long-term use of drugs, such as long-term use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) will cause gastric ulcers and impaired kidney function. In OA pathogenesis, PGE2 gene is involved in the inflammation process.

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