Obstetric Outcome in Pregnant Patients with Low Level of Pregnancy-Associated Plasma Protein A in First Trimester | Zendy

Vesna Livrinova | Zendy; Igor Petrov | Zendy; Igor Samardziski | Zendy; Viktorija Jovanovska | Zendy; Slagjana Simeonova-Krstevska | Zendy; Irena Todorovska | Zendy; Aleksandra Atanasova-Boshku | Zendy; Milena Gjeorgjievska | Zendy

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Obstetric Outcome in Pregnant Patients with Low Level of Pregnancy-Associated Plasma Protein A in First Trimester

Author(s) -

Vesna Livrinova,

Igor Petrov,

Igor Samardziski,

Viktorija Jovanovska,

Slagjana Simeonova-Krstevska,

Irena Todorovska,

Aleksandra Atanasova-Boshku,

Milena Gjeorgjievska

Publication year - 2018

Publication title -

open access macedonian journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.288

H-Index - 17

ISSN - 1857-9655

DOI - 10.3889/oamjms.2018.238

Subject(s) - medicine , pregnancy associated plasma protein a , obstetrics , pregnancy , placental abruption , preeclampsia , intrauterine growth restriction , fetus , gynecology , first trimester , biology , genetics

Pregnancy-associated plasma protein A (PAPP-A), is a protease which releases Insulin-like growth factor. The role of this factor is stimulation of cell mitosis, differentiation and trophoblastic invasion of deciduas. Identification of patients with low PAPP-A (under 0.4 MoM in the first trimester has an influence on birth weight, attenuation of fetal growth, preeclampsia, birth and fetal demise.

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