Forced Diuresis and Expedient Blood Pressure Control in the Management of Quetiapine Induced Neuroleptic Malignant Syndrome: A Case Report | Zendy

Neville Aquilina | Zendy; Vincent Bugeja | Zendy

Open Access

Forced Diuresis and Expedient Blood Pressure Control in the Management of Quetiapine Induced Neuroleptic Malignant Syndrome: A Case Report

Author(s) -

Neville Aquilina,

Vincent Bugeja

Publication year - 2018

Publication title -

open access macedonian journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.288

H-Index - 17

ISSN - 1857-9655

DOI - 10.3889/oamjms.2018.160

Subject(s) - medicine , rhabdomyolysis , neuroleptic malignant syndrome , blood pressure , renal function , bumetanide , diuresis , anesthesia , gastroenterology , urology , cotransporter , chemistry , organic chemistry , sodium

This case report intends to highlight the importance of safeguarding renal function from rhabdomyolysis in neuroleptic malignant syndrome (NMS) by concomitant administration of parenteral fluids at a high rate together with high doses of parenteral loop diuretics (we utilised 6 mg bumetanide daily) and tailed over a few days, in order to preserve glomerular/renal medullary perfusion and nephron function.

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