CD33+ HLA-DR– Myeloid-Derived Suppressor Cells Are Increased in Frequency in the Peripheral Blood of Type1 Diabetes Patients with Predominance of CD14+ Subset | Zendy

Mirhane Hassan | Zendy; Hala M. Raslan | Zendy; Hesham Gamal Eldin | Zendy; Eman Mahmoud | Zendy; Hanaa Alm-Elhuda Abd Elwajed | Zendy

Open Access

CD33+ HLA-DR– Myeloid-Derived Suppressor Cells Are Increased in Frequency in the Peripheral Blood of Type1 Diabetes Patients with Predominance of CD14+ Subset

Author(s) -

Mirhane Hassan,

Hala M. Raslan,

Hesham Gamal Eldin,

Eman Mahmoud,

Hanaa Alm-Elhuda Abd Elwajed

Publication year - 2018

Publication title -

open access macedonian journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.288

H-Index - 17

ISSN - 1857-9655

DOI - 10.3889/oamjms.2018.080

Subject(s) - medicine , myeloid derived suppressor cell , cd14 , cd33 , type 1 diabetes , immunology , diabetes mellitus , nephropathy , population , diabetic nephropathy , flow cytometry , immune system , human leukocyte antigen , hla dr , suppressor , endocrinology , antigen , stem cell , cancer , biology , environmental health , cd34 , genetics

Type 1 Diabetes Mellitus (T1D) is an autoimmune disease that results from the destruction of insulin-producing beta cells of the pancreas by autoreactive T cells. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that can potently suppress T cell responses.

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