Expression of E-Cadherin/Beta-Catenin in Epithelial Carcinomas of the Thyroid Gland | Zendy

Koni Ivanova | Zendy; Julian Ananiev | Zendy; Elina Aleksandrova | Zendy; M. Ignatova | Zendy; Maya Gulubova | Zendy

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Expression of E-Cadherin/Beta-Catenin in Epithelial Carcinomas of the Thyroid Gland

Author(s) -

Koni Ivanova,

Julian Ananiev,

Elina Aleksandrova,

M. Ignatova,

Maya Gulubova

Publication year - 2017

Publication title -

open access macedonian journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.288

H-Index - 17

ISSN - 1857-9655

DOI - 10.3889/oamjms.2017.043

Subject(s) - medicine , thyroid , pathology , immunohistochemistry , catenin , cadherin , carcinogenesis , wnt signaling pathway , follicular phase , thyroid cancer , cancer research , cancer , cell , biology , signal transduction , biochemistry , genetics

The aberrant activation of Wnt signalling pathway may be a common denominator for the development of thyroid tumorigenesis. It was announced that the loss of E-cadherin rather than β-catenin mutation represents a crucial event in determining the degree of differentiation of thyroid carcinomas.

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