Expression of ERG Protein and TMRPSS2-ERG Fusion in Prostatic Carcinoma in Egyptian Patients | Zendy

Ahmed M. Abdelhady | Zendy; Ali ElHindawi | Zendy; Olfat Hammam | Zendy; Heba Khalil | Zendy; Sara Diab | Zendy; Soulafa Abd El-Aziz | Zendy; Mohamed Badawy | Zendy; Ahmed Shehata Ismail | Zendy; Noha A.H. Helmy | Zendy; Nora N. Kamel | Zendy; Shady E. Anis | Zendy; Amr El Kholy | Zendy; Khalid Al Osili | Zendy; Afaf Ahmed Abdel-Hady | Zendy; Hani H. Nour | Zendy; Maha Akl | Zendy

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Expression of ERG Protein and TMRPSS2-ERG Fusion in Prostatic Carcinoma in Egyptian Patients

Author(s) -

Ahmed M. Abdelhady,

Ali ElHindawi,

Olfat Hammam,

Heba Khalil,

Sara Diab,

Soulafa Abd El-Aziz,

Mohamed Badawy,

Ahmed Shehata Ismail,

Noha A.H. Helmy,

Nora N. Kamel,

Shady E. Anis,

Amr El Kholy,

Khalid Al Osili,

Afaf Ahmed Abdel-Hady,

Hani H. Nour,

Maha Akl

Publication year - 2017

Publication title -

open access macedonian journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.288

H-Index - 17

ISSN - 1857-9655

DOI - 10.3889/oamjms.2017.037

Subject(s) - erg , medicine , tmprss2 , immunohistochemistry , carcinoma , pathology , fusion gene , prostate cancer , cancer , gene , ophthalmology , biology , genetics , retinal , disease , covid-19 , infectious disease (medical specialty)

Prostate cancer (PCa) is the second most common cancers in men worldwide. Its incidence can be influenced by several risk factors including genetic susceptibility. Therefore the search for the expression of a certain gene (ERG) and its rearrangement could give us clues for proper identification of PCa. And the study of ERG expression and its comparison to FISH in Egyptian patients can show whether ERG immunophenotype could be used instead of FISH, as it is cheaper.

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