Expression Levels of Some Detoxification Genes in Liver and Testis of Rats Exposed to a Single Dose of Methyl-Tertiary Butyl Ether | Zendy

Ahmad Ali Badr | Zendy; Mostafa Saadat | Zendy

Open Access

Expression Levels of Some Detoxification Genes in Liver and Testis of Rats Exposed to a Single Dose of Methyl-Tertiary Butyl Ether

Author(s) -

Ahmad Ali Badr,

Mostafa Saadat

Publication year - 2016

Publication title -

open access macedonian journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.288

H-Index - 17

ISSN - 1857-9655

DOI - 10.3889/oamjms.2016.057

Subject(s) - gstp1 , glutathione , medicine , antioxidant , gene , andrology , ether , enzyme , gene expression , toxicology , endocrinology , physiology , biochemistry , biology , chemistry , organic chemistry

Methyl-tertiary-butyl ether (MTBE), a well-known gasoline oxygenate compound, is still used in several countries. Several studies investigated the effects of MTBE on the activity of phase II metabolism enzymes. There is no published data on the effect(s) of short-term exposure to MTBE on mRNA levels of antioxidant genes. Therefore, the present study was carried out.

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