Detection of BCR/ABL Translocation in Bone Marrow Derived Mesenchymal Stem Cells in Egyptian CML Patients | Zendy

Taghrid Gaafar | Zendy; Inas Raafat | Zendy; Azza A. Aly | Zendy; Nagwa Mohamed | Zendy; Reem Jan Farid | Zendy; Nevine E. Saad | Zendy; Rabab El Hawary | Zendy; Naglaa Mostafaa | Zendy; Mirhan Mohamed Ahmed | Zendy

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Detection of BCR/ABL Translocation in Bone Marrow Derived Mesenchymal Stem Cells in Egyptian CML Patients

Author(s) -

Taghrid Gaafar,

Inas Raafat,

Azza A. Aly,

Nagwa Mohamed,

Reem Jan Farid,

Nevine E. Saad,

Rabab El Hawary,

Naglaa Mostafaa,

Mirhan Mohamed Ahmed

Publication year - 2015

Publication title -

open access macedonian journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.288

H-Index - 17

ISSN - 1857-9655

DOI - 10.3889/oamjms.2015.040

Subject(s) - mesenchymal stem cell , medicine , stem cell , bone marrow , cancer research , haematopoiesis , chromosomal translocation , myeloid leukemia , philadelphia chromosome , immunology , pathology , biology , microbiology and biotechnology , gene , genetics

Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of hematopoietic stem cells. It is characterized at the cytogenetic level by Philadelphia (ph) chromosome and at the molecular level by the BCR/ABL gene rearrangement. Bone marrow derived mesenchymal stem cells (MSCs) are pluripotent stem cells that can differentiate into several mesenchymal tissues.

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