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Significance of Serum Cytokeratin-18 in Prediction of Hepatocellular Carcinoma in Chronic Hepatitis C Infected Egyptian Patients
Author(s) -
Wafaa M. El-Zefzafy,
Hanan M. El-Tokhy,
Nagwa Mohamed,
Zakia Abu-Zahab
Publication year - 2015
Publication title -
open access macedonian journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.288
H-Index - 17
ISSN - 1857-9655
DOI - 10.3889/oamjms.2015.021
Subject(s) - medicine , hepatocellular carcinoma , cytokeratin , chronic hepatitis , clinical significance , gastroenterology , carcinoma , hepatitis , pathology , virology , immunohistochemistry , virus
Hepatitis C virus is one of the most common etiologic agents of chronic liver diseases, including liver cirrhosis and hepatocellular carcinoma in which there is continuous inflammation and regeneration of hepatocytes. Cytokeratin-18 (CK18) has been suggested to play an important role in tumorigenesis of epithelial cancers.

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