Bacterial profile and antibiogram of blood stream infections in febrile neutropenic patients with haematological malignancies
Author(s) -
Prathyusha Kokkayil,
Reshu Agarwal,
Sarita Mohapatra,
Sameer Bakshi,
Bimal Kumar Das,
Seema Sood,
Benu Dhawan,
Arti Kapil
Publication year - 2018
Publication title -
the journal of infection in developing countries
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 49
eISSN - 2036-6590
pISSN - 1972-2680
DOI - 10.3855/jidc.9725
Subject(s) - medicine , neutropenia , drug resistance , tazobactam , piperacillin , colistin , klebsiella pneumoniae , sulbactam , blood culture , febrile neutropenia , enterobacter , antibiotics , antibiotic resistance , microbiology and biotechnology , imipenem , biology , bacteria , pseudomonas aeruginosa , escherichia coli , chemotherapy , biochemistry , genetics , gene
Studies have shown a shift in the prevalence from Gram-positive to Gram-negative bacteraemia in patients with haematological malignancies who develop febrile neutropenia. There are also reports on the spread of drug resistant bacteria among these patients. Information about locally prevalent bacteria and their resistance is important to guide empirical therapy. The aim of this study was to characterise the bacterial spectrum and antibiotic resistance pattern of bacteraemia in neutropenic patients with haematological malignancies METHODOLOGY: In this retrospective study, patients admitted to Haematology and Oncology units over a period of 6 months with laboratory-confirmed positive blood cultures were enrolled. Information regarding demographic profile, clinical features, and microbiological profile were recorded. Standard procedures were applied to identify the isolates and their resistance patterns. The data collected was analysed statistically.
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