Association of vitamin D binding protein polymorphisms with response to therapy in Egyptian chronic hepatitis C patients
Author(s) -
Ahmed Kamel,
Samar Farid,
Ahmed S. Attia,
Maissa El Raziky
Publication year - 2017
Publication title -
the journal of infection in developing countries
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 49
eISSN - 2036-6590
pISSN - 1972-2680
DOI - 10.3855/jidc.8830
Subject(s) - chronic hepatitis , medicine , gastroenterology , vitamin d binding protein , vitamin , vitamin d and neurology , immunology , virus
Vitamin D binding protein (VDBP) is a potential modulator of immune response and is associated with clinical progression of many diseases. Our aim was to assess influence of baseline 25-hydroxyvitamin D levels and VDBP single nucleotide polymorphisms (SNPs), rs4588 (C > A) and rs7041 (G > T), on baseline clinical parameters and response to interferon based therapy in chronic hepatitis C patients in Egypt.
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