Mycobacterium tuberculosis strains from ancient and modern lineages induce distinct patterns of immune responses | Zendy

Pampi Chakraborty | Zendy; Savita Kulkarni | Zendy; Ramakrishna Rajan | Zendy; Krishna B. Sainis | Zendy

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Mycobacterium tuberculosis strains from ancient and modern lineages induce distinct patterns of immune responses

Author(s) -

Pampi Chakraborty,

Savita Kulkarni,

Ramakrishna Rajan,

Krishna B. Sainis

Publication year - 2018

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.8596

Subject(s) - mycobacterium tuberculosis , immune system , biology , tuberculosis , microbiology and biotechnology , mycobacterium , immunology , virology , medicine , bacteria , genetics , pathology

It is possible that the difference in virulence and prevalence of different strains of Mycobacterium tuberculosis is related to the diverse immune response they evoke in the host. Outbreak strains have been shown to subvert the innate immune response as a potential host evasion mechanism. However, the immunological outcome of the interactions of different clinical strains with different host cells is still not understood.

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