Single nucleotide polymorphisms of interleukins associated with hepatitis C virus infection in Egypt | Zendy

Hany Khalil | Zendy; Mohamed Arfa | Zendy; Samir El-Masrey | Zendy; Sherif M. ElSherbini | Zendy; Amal AbdelAziz | Zendy

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Single nucleotide polymorphisms of interleukins associated with hepatitis C virus infection in Egypt

Author(s) -

Hany Khalil,

Mohamed Arfa,

Samir El-Masrey,

Sherif M. ElSherbini,

Amal AbdelAziz

Publication year - 2017

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.8127

Subject(s) - viremia , hepatitis c virus , single nucleotide polymorphism , genotype , biology , virology , hepatitis c , immunology , interleukin , virus , interleukin 10 , liver disease , gene , cytokine , genetics , biochemistry

Hepatitis C is a liver disease caused by the hepatitis C virus (HCV). It can cause both acute and chronic hepatitis infection. Based on secretion of required cytokines upon infection, HCV can improve its own RNA and successfully complete the replication cycle. Importantly, single nucleotide polymorphisms (SNPs) are the most common type of genetic variation and have been found to play a critical role in modulation of cellular cytokine production and interaction.

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