English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Dear Editor, Acute infectious diarrhoea continues to be a significant cause of morbidity and mortality in children in low income countries. Among bacterial isolates, Shigella spp and Salmonella spp are known to contribute to the high burden of this illness in children. Recent literature survey reveals a sharp declining of prevalence of S. Typhi, while non-typhoidal Salmonella (NTS) and Shigella flexneri are increasing [1]. Among the Shigella isolates, > 90% are resistant to ampicillin and sulfonamides [2], 4%–10% of isolates are resistant to at least one of the thirdgeneration cephalosporins (ceftriaxone/cefotaxime) [3,2], and 7%–33% to fluoroquinolones [2]. Whereas in NTS, 86% are resistant to ampicillin, 33%–48% to sulfonamides [4,5], 34% to third-generation cephalosporins [3], and 24%-35% to fluoroquinolones [4,5]. Monitoring of cephalosporins and fluoroquinolones resistance is particularly important because these antibiotics are among the few therapeutic options commonly used for moderate to severe Salmonella and Shigella infections. The objective of this study was to determine the co-existence of qnr and extended-spectrum β lactamase (ESBL) genes in clinical isolates of multidrug-resistant (MDR) Shigella spp and Salmonella spp. (defined here as isolates resistant to ≥ 3 drugs)

Association of blaCTX-M-15 and qnr genes in multidrug-resistant Salmonella Typhimurium and Shigella spp from India