Expression of Toll-like receptor (TLR) 2 and TLR4 in the livers of mice infected by Clonorchis sinensis | Zendy

Chao Yan | Zendy; Xiangyang Li | Zendy; Bo Li | Zendy; Beibei Zhang | Zendy; Jiangtao Xu | Zendy; Hui Hua | Zendy; Qian Yu | Zendy; Zhuan-Zhuan Liu | Zendy; Linlin Fu | Zendy; Renxian Tang | Zendy; Kuiyang Zheng | Zendy

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Expression of Toll-like receptor (TLR) 2 and TLR4 in the livers of mice infected by Clonorchis sinensis

Author(s) -

Chao Yan,

Xiangyang Li,

Bo Li,

Beibei Zhang,

Jiangtao Xu,

Hui Hua,

Qian Yu,

Zhuan-Zhuan Liu,

Linlin Fu,

Renxian Tang,

Kuiyang Zheng

Publication year - 2015

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.6698

Subject(s) - clonorchis sinensis , tlr2 , clonorchiasis , biology , tlr4 , toll like receptor , immune system , receptor , interleukin 18 , innate immune system , immunology , microbiology and biotechnology , cytokine , helminths , biochemistry

Clonorchis sinensis is one of the most important foodborne pathogens in humans, and can cause biliary diseases such as gallstones, cholecystitis, cholangitis, and cholangiocarcinoma. Toll-like receptors (TLRs) as sensors are crucial to initiating both innate and adaptive immune defenses against pathogens. However, little is known about the hepatic expression of TLRs of hosts induced by C. sinensis infection.

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