Prevalence of H. pylori in gastric biopsy specimen in the southeastern region of Turkey | Zendy

Fulya Bayındır Bilman | Zendy; Mehmet Özdemir | Zendy; Birol Baysal | Zendy; Muhammed Güzel Kurtoğlu | Zendy

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Prevalence of H. pylori in gastric biopsy specimen in the southeastern region of Turkey

Author(s) -

Fulya Bayındır Bilman,

Mehmet Özdemir,

Birol Baysal,

Muhammed Güzel Kurtoğlu

Publication year - 2016

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.6690

Subject(s) - caga , helicobacter pylori , gastritis , gastric mucosa , virulence , cancer , biopsy , stomach , polymerase chain reaction , atrophic gastritis , spirillaceae , pathogenesis , gastroenterology , medicine , microbiology and biotechnology , gene , biology , genetics

Helicobacter pylori is a Gram-negative, microaerophilic bacterium that colonizes human gastric mucosa. Gastric ulcer, duodenal ulcer, chronic atrophic gastritis, mucosa-associated lymphoid tissue lymphoma, and stomach adenocarcinoma are associated with H. pylori as the etiological agent. Cytotoxin-associated gene A (cagA), which is one of the most important virulence factors of H. pylori, encodes a 120-145 kDa protein. The prevalence of cagA genes shows differences in H. pylori infections based on geographical area, and cagA-positive H. pylori strains play an important role in pathogenesis of gastric carcinoma.

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