Correlation of quorum sensing and virulence factors in Pseudomonas aeruginosa isolates in Egypt | Zendy

Hamida Abou-Shleib | Zendy; Hoda Omar | Zendy; Rania Abozahra | Zendy; Amel Elsheredy | Zendy; Kholoud Baraka | Zendy

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Correlation of quorum sensing and virulence factors in Pseudomonas aeruginosa isolates in Egypt

Author(s) -

Hamida Abou-Shleib,

Hoda Omar,

Rania Abozahra,

Amel Elsheredy,

Kholoud Baraka

Publication year - 2015

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.6492

Subject(s) - quorum sensing , pseudomonas aeruginosa , virulence , microbiology and biotechnology , biology , bacteria , genetics , gene

Pseudomonas aeruginosa is one of the most virulent nosocomial pathogens worldwide. Quorum sensing (QS) regulates the production of pathogenic virulence factors and biofilm formation in P. aeruginosa. The four genes lasR, lasI, rhlR,and rhlI were found to regulate this QS system. In this study, we aimed to assess the correlation between these four genes and QS-dependent virulence factors and to detect the inhibitory effect of clove oil on QS.

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