Protein-protein interactions between A. aegypti midgut and dengue virus 2: two-hybrid screens using the midgut cDNA library | Zendy

Hong-Wai Tham | Zendy; Vinod Balasubramaniam | Zendy; Miaw-Fang Chew | Zendy; Hamdan Ahmad | Zendy; Sharifah Syed Hassan | Zendy

Open Access

Protein-protein interactions between A. aegypti midgut and dengue virus 2: two-hybrid screens using the midgut cDNA library

Author(s) -

Hong-Wai Tham,

Vinod Balasubramaniam,

Miaw-Fang Chew,

Hamdan Ahmad,

Sharifah Syed Hassan

Publication year - 2015

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.6422

Subject(s) - midgut , dengue virus , dengue fever , virology , cdna library , complementary dna , aedes aegypti , biology , virus , gene , biochemistry , botany , larva

Dengue virus (DENV) is principally transmitted by the Aedes aegypti mosquito. To date, mosquito population control remains the key strategy for reducing the continuing spread of DENV. The focus on the development of new vector control strategies through an understanding of the mosquito-virus relationship is essential, especially targeting the midgut, which is the first mosquito organ exposed to DENV infection.

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