Role of efflux pumps inhibitor in decreasing antibiotic resistance of Klebsiella pneumoniae in a tertiary hospital in North India | Zendy

Joel Filgona | Zendy; Tuhina Banerjee | Zendy; Shampa Anupurba | Zendy

Open Access

Role of efflux pumps inhibitor in decreasing antibiotic resistance of Klebsiella pneumoniae in a tertiary hospital in North India

Author(s) -

Joel Filgona,

Tuhina Banerjee,

Shampa Anupurba

Publication year - 2015

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.6216

Subject(s) - ertapenem , tigecycline , doripenem , microbiology and biotechnology , colistin , klebsiella pneumoniae , efflux , meropenem , biology , multiple drug resistance , carbapenem , drug resistance , antibiotics , antibiotic resistance , escherichia coli , biochemistry , genetics , gene

The contribution of efflux systems to drug resistance in Enterobacteriaceae is becoming increasingly appreciated. This study phenotypically analyzed the role of efflux mechanisms in resistance to ertapenem, doripenem, and tigecycline among clinical isolates of carbapenem-resistant Klebsiella pneumoniae (CRKP).

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