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A hospital based pilot study on Epstein-Barr virus in suspected infectious mononucleosis pediatric patients in India
Author(s) -
Janani Madhuravasal Krishnan,
Jambulingam Malathi,
Andal Appaswamy,
Nishi Rani Singha,
Hajib Nariharirao Madhavan
Publication year - 2015
Publication title -
the journal of infection in developing countries
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 49
eISSN - 2036-6590
pISSN - 1972-2680
DOI - 10.3855/jidc.6199
Subject(s) - mononucleosis , epstein–barr virus , serology , virology , virus , polymerase chain reaction , cytomegalovirus , antibody , epstein–barr virus infection , real time polymerase chain reaction , medicine , immunology , herpesviridae , biology , viral disease , gene , biochemistry
Infectious mononucleosis (IM) caused by the Epstein-Barr virus (EBV) is commonly diagnosed by detection of antibodies in the patient's sera. Differentiation of acute from chronic and differential diagnosis of EBV-induced IM from IM-like syndrome caused by human cytomegalovirus (CMV) is important. The objective of this study was to standardize and use polymerase chain reaction (PCR) for diagnosis of EBV and evaluate it against enzyme-linked immunosorbent assay (ELISA).

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