Prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency in southeast Iran: implications for malaria elimination | Zendy

Seyed Mehdi Tabatabaei | Zendy; Alireza Salimi Khorashad | Zendy; Mohammad Sakeni | Zendy; Ahmad Raeisi | Zendy; Zahra Metanat | Zendy

Open Access

Prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency in southeast Iran: implications for malaria elimination

Author(s) -

Seyed Mehdi Tabatabaei,

Alireza Salimi Khorashad,

Mohammad Sakeni,

Ahmad Raeisi,

Zahra Metanat

Publication year - 2015

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.5572

Subject(s) - primaquine , malaria , glucosephosphate dehydrogenase deficiency , glucose 6 phosphate dehydrogenase , medicine , hemolysis , glucose 6 phosphate dehydrogenase deficiency , plasmodium vivax , physiology , immunology , biology , dehydrogenase , plasmodium falciparum , enzyme , biochemistry , chloroquine

Glucose-6-phosphate dehydrogenase deficiency (G6PD) is an X-linked genetic disorder with a relatively high frequency in malaria-endemic regions. It is an obstacle to malaria elimination, as primaquine administered in the treatment of malaria can cause hemolysis in G6PD-deficient individuals. This study presents information on the prevalence of G6PD deficiency in Sistan and Balouchetsan province, which hosts more than 90% of Plasmodium vivax malaria cases in Iran. This type of information is needed for a successful malaria elimination program.

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