Deletion, insertion and stop codon mutations in vif genes of HIV-1 infecting slow progressor patients | Zendy

Héctor R. Rangel | Zendy; Domingo Garzaro | Zendy; Anny Karely Rodríguez | Zendy; Alvaro Ramı́rez | Zendy; Gladys Ameli | Zendy; Cristina Del Rosario Gutiérrez | Zendy; Flor H. Pujol | Zendy

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Deletion, insertion and stop codon mutations in vif genes of HIV-1 infecting slow progressor patients

Author(s) -

Héctor R. Rangel,

Domingo Garzaro,

Anny Karely Rodríguez,

Alvaro Ramı́rez,

Gladys Ameli,

Cristina Del Rosario Gutiérrez,

Flor H. Pujol

Publication year - 2009

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.471

Subject(s) - stop codon , gene , biology , virology , mutation , strain (injury) , genetics , human immunodeficiency virus (hiv) , anatomy

Variable progression towards AIDS has been described and has been related to viral and host factors. Around 10% of the HIV-1 infected patients are slow progressors (SP), not presenting with AIDS disease signs even after more than 10 years of infection. Viral gene defects have been associated with the disease progression but more studies are still needed.

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