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High Level of Resistance to nalidixic acid in Salmonella enterica serovar Typhi in Central India
Author(s) -
Yashwant Kumar,
Anshu Sharma,
Kavaratty Raju Mani
Publication year - 2009
Publication title -
the journal of infection in developing countries
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 49
eISSN - 2036-6590
pISSN - 1972-2680
DOI - 10.3855/jidc.419
Subject(s) - nalidixic acid , ciprofloxacin , salmonella typhi , minimum inhibitory concentration , typhoid fever , microbiology and biotechnology , salmonella , salmonella enterica , biology , bacteria , escherichia coli , antibiotics , biochemistry , genetics , gene
Fluoroquinolones are the drugs of choice for the treatment of typhoid fever. But the recent increase in minimum inhibitory concentration (MIC) values of ciprofloxacin in Salmonella Typhi may result in delayed response and serious complications. Nalidixic acid resistance has been used as an indirect evidence of increased minimum inhibitory concentration for ciprofloxacin in Salmonella Typhi.

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