Passaging impact of H9N2 avian influenza virus in hamsters on its pathogenicity and genetic variability | Zendy

Houssam Shaib | Zendy; N. Cochet | Zendy; Thierry Ribeiro | Zendy; Afif M. Abdel Nour | Zendy; Georges Nemer | Zendy; Esam I. Azhar | Zendy; Archana Iyer | Zendy; Taha Kumosani | Zendy; Steve Harakeh | Zendy; Elie K. Barbour | Zendy

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Passaging impact of H9N2 avian influenza virus in hamsters on its pathogenicity and genetic variability

Author(s) -

Houssam Shaib,

N. Cochet,

Thierry Ribeiro,

Afif M. Abdel Nour,

Georges Nemer,

Esam I. Azhar,

Archana Iyer,

Taha Kumosani,

Steve Harakeh,

Elie K. Barbour

Publication year - 2014

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.4023

Subject(s) - virology , biology , neuraminidase , virus , hamster , hemagglutinin (influenza) , influenza a virus subtype h5n1 , microbiology and biotechnology

Avian influenza viruses of the H9N2 subtype have been reported to cause human infections. This study demonstrates the impact of nasal viral passaging of avian H9N2 in hamsters on its cross species-pathogenic adaptability and variability of amino acid sequences of the hemagglutinin (HA) and neuraminidase (NA) stalk.

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